欧盟评估葡糖基橙皮苷作为新型食物的平安性时候：2024-08-09 10:07来历：食物火伴网作者： 泽夕 焦点提醒：2024年8月8日，据欧盟食物平安局（EFSA）动静，欧盟营养、新型食物和食品过敏原（NDA）研究小组就葡糖基橙皮苷（glucosyl hesperidin）作为新型食物的平安性颁发科学定见。 食物火伴网讯 2024年8月8日，据欧盟食物平安局（EFSA）动静，欧盟营养、新型食物和食品过敏原（NDA）研究小组就葡糖基橙皮苷（glucosyl hesperidin）作为新型食物的平安性颁发科学定见。 颠末评估，专家小组得出结论，在提议的利用前提下，葡糖基橙皮苷作为新型食物是平安的。部门原文报导以下： Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on glucosyl hesperidin (GH) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF, which is produced from hesperidin and dextrin by enzymatic reactions, is a powder consisting mainly of monoglucosyl hesperidin (MGH) and unreacted hesperidin (flavonoid), which account in total for up to 92.8% (on dry basis) of the product. The applicant proposed to use the NF in specific drinks and food supplements leading to a maximum intake of up to 364 mg per day for adults. The target population is the general population, except for food supplements for which the proposed target population is children from 1 year onwards and adults. Taking into consideration the composition of the NF and the proposed uses, the consumption of the NF is not nutritionally disadvantageous. There are no concerns regarding genotoxicity of the NF. based on a 90-day oral toxicity study conducted with the NF, the Panel considers the NOAEL at the mid-dose group, i.e. ~ 1000 mg/kg body weight (bw) per day. By applying an uncertainty factor of 200, the resulting intake providing sufficient margin of exposure for humans would be 5 mg/kg bw per day. The available human intervention studies did not report clinically relevant changes in haematological or clinical chemistry parameters following the administration of GH/MGH at supplemental doses of up to 3 g/day for 12 weeks. Overall, the Panel considers that the margin of exposure (~ 200) between the intake of the NF at the proposed uses and use levels and the NOAEL from the 90-day study is sufficient. The Panel concludes that the NF, glucosyl hesperidin, is safe for the target population at the proposed uses and use levels. 本文由食物火伴网食物资讯中间编纂，供网友参考，有任何疑问，请联系news@foodmate.net。